Abstract

Abstract Small fragments of tumor DNA can be found in the blood circulation and can be monitored and analysed as part of a novel cancer detection method known as circulating tumor DNA (ctDNA). These tumor DNA fragments can be isolated and quantified to produce detailed information related to cancer progression and treatment responses in patients. The possibility of utilizing a simple blood sample to allow detection and monitoring of cancer growth and behavior is highly desirable given that gaining access to and obtaining biopsy samples from solid cancers in people is not always possible or as straightforward as needed. It is anticipated this simple method of detecting and monitoring cancer will enhance the precision of cancer care for patients, and will eventuate into a particularly useful tool within resource constrained environments. The purpose of this work was to identify the diagnostic methods, treatment and pharmacological options currently available for cancer patients within the Socialist Republic of Vietnam and to explore the potential utility and applicability of ctDNA as a mechanism to support the management, treatment and diagnosis of cancer patients. Favorable interest was expressed by medical, health, community and lay persons regarding the development of ctDNA as a potential diagnostic tool within the health setting in the Socialist Republic of Vietnam and remains an attractive tool with potential to support cancer patients in Vietnam.

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