Abstract
Abstract A novel cancer detection method known as circulating tumour DNA (ctDNA) monitors small fragments of tumour DNA found in the blood circulation. These fragments can be isolated and quantified to obtain data related to cancer progression and treatment response. Since gaining access to and obtaining biopsy samples from solid cancers in people is not always possible or straightforward, the possibility of utilizing a simple blood sample to allow detection and monitoring of cancer growth and behaviour is highly desirable. It is anticipated this simple method of detecting and monitoring cancer will enhance the precision of cancer care for patients, and will eventuate into a particularly useful tool within resource constrained environments such as the Pacific. The purpose of this work was to explore the potential utility of ctDNA to support the management, treatment and diagnosis of cancer patients in Samoa and identify the diagnostic methods, treatment and pharmacologic options currently available for cancer patients. Strong interest was expressed by medical, nursing, health and community research staff and lay persons in the development of ctDNA particularly as a potential diagnostic tool within the health setting in Samoa. A key feature of interest concerning the ctDNA technology was the potential to monitor patients in remote locations by visiting them in their homes rather than having them travel to the main hospitals often with their families. ctDNA remains an attractive tool with potential to support cancer patients in Samoa.
Published Version
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