The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl

Carolina R Biasetto,Andressa Somensi,Renata Sordi,Vanessa M Chapla,Samad N Ebrahimi,Geraldo H Silva,Helder L Teles,Vanderlan Da S Bolzani,Maria Cláudia M Young,Ludwig H Pfenning,Angela R Araujo

doi:10.1016/j.phytol.2020.01.019

The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl

Carolina R Biasetto, Andressa Somensi + Show 9 more

https://doi.org/10.1016/j.phytol.2020.01.019

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Journal: Phytochemistry letters	Publication Date: Feb 7, 2020
Citations: 8

Affiliation: Universidade Estadual Paulista (Unesp), Universidade Federal do Tocantins, Shahid Beheshti University, Universidade Federal de Viçosa, Universidade Federal de Mato Grosso, Instituto de Botânica, Universidade Federal de Lavras

#TLC Bioautographic Assays #Structures Of Polyketides + Show 8 more

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Abstract

Two new polyketides, named koninginin T (1) and U (2), were isolated from Phomopsis stipata - an endophytic fungus isolated from Styrax camporum Pohl. The structures of polyketides 1 and 2 were defined through the analysis of spectroscopic data. Antifungal and acetylcholinesterase inhibitory activities of these compounds were evaluated using TLC bioautographic assays. Compounds 1 and 2 displayed moderate antifungal activity and compound 1 showed acetylcholinesterase inhibitory activity.

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