Abstract
According to different authors, the osteoarticular syndrome is observed in every third patient with acute leukemia. The polymorphism of the clinical manifestations presents a diagnostic difficulty, while the abnormal x-ray findings are not traditional characteristics of patients with leukemia. In some cases, bone manifestations may be the first and only symptom of acute lymphoblastic leukemia, complicating the diagnosis and postponing the correct diagnosis. The article describes 3 clinical cases of patients with a lesion of the osteo-articular system in the onset of acute leukemia. Despite the current complex laboratory and instrumental research methods, a particular attention should be paid to the difficulties of differential diagnosis between acute leukemia and other lesions of the osteo-articular system.
Highlights
The osteoarticular syndrome is observed in every third patient with acute leukemia
Despite the current complex laboratory and instrumental research methods, a particular attention should be paid to the difficulties of differential diagnosis between acute leukemia and other lesions of the osteo-articular system
Представленные клинические случаи демонстрируют, что поражение костно-суставной системы при дебюте острого лимфоидного лейкоза способствует удлинению диагностического этапа и поздней постановке корректного диагноза, что в свою очередь влияет на результаты лечения
Summary
The osteoarticular syndrome is observed in every third patient with acute leukemia. The article describes 3 clinical cases of patients with a lesion of the osteo-articular system in the onset of acute leukemia. Поражения костной системы при дебюте острого лимфоидного лейкоза разнообразны и включают Выжлецова» диагноз острого лимфоидного лейкоза был установлен у 53 детей.
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