Abstract
The influence of human head tissue properties on intracranial pressure response during direct head impact was studied using finite element analysis and Design-of-Experiment (DOE) techniques. A three-factor, three-level factorial experiment design was applied to the skull, cerebrospinal fluid and brain of a finite element human head model to characterise the effects of these tissues on intracranial pressure response of the human head. This study has demonstrated that a DOE approach can provide more modelling information than the approach using one factor at a time. It has also shown that the incompressibility of the brain contributes much more to the variability of coup and contrecoup pressures than other cranial contents (73% and 53%, respectively).
Published Version
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