Abstract
Personal security is one of the important components of Russian national security. A serious challenge to the existential security of the individual comes from modern biomedical and information technologies, the use of which creates opportunities for changing the biosocial nature of a person. The distortion of the moral content of the philosophical principle of humanism in the conditions of the Fourth Industrial Revolution gave rise to the spread of the philosophy and ideology of transhumanism and post-humanism. The introduction of Trans-human and Post-human images into the public consciousness is a global threat to the continued existence of mankind.
 Purpose is to trace the historical transformation of the philosophy of humanism, which led to the formation of modern concepts of Trans-human and Post-human.
 Methodology: the article uses the methodology of historical and philosophical research approaches.
 Results:
 1) A brief overview of the evolution of understanding of the essence of man and the principle of humanism in the history of philosophical thought is given.
 2) The danger of deepening the gap between man and the technologies he creates is shown, especially in the conditions of the Fourth Industrial Revolution.
 3) The content of the ideology and philosophy of transhumanism is revealed.
 4) Various images of the Post-human, replacing Homo Sapiens, are considered.
 5) The possible negative consequences for humanity of attempts to artificially change human nature are indicated.
 Practical implications: scientific discussions, expert activity, educational process.
 Conclusions:
 1) A serious challenge to the security of the individual in modern society is the implementation in practice of the ideas of «cybernetic evolution», which call into question the continuation of human existence as a biological species.
 2) The philosophy of classical humanism, based on the recognition of human life as the highest ethical value, is being blurred and distorted today.
 3) Advances in the development of biomedical and information technologies have created favorable opportunities for attempts to revise the very nature of man in order to prolong life expectancy and overcome mortality, which was expressed in the concepts of Trans-human and Post-human.
 4) The philosophy of transhumanism and post-humanism consistently leads to the destruction of the human personality.
 5) The task of global management of post-humanity is greatly facilitated by the use of genetic and information technologies.
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