The impact of water and ionic liquid on the structure and stability of biomolecules

Abstract

Biological water molecules are the major driving forces for the stability of biomolecules. The hydration patterns around the biomolecules stabilize the proteins and nucleic acids. Also, ionic liquids (ILs) can be utilized for biomolecular stabilizers and drug delivery applications by interacting with water and biomolecules. Getting more insights into various interactions of water and ILs with biomolecules are very essential to recognize the functions of biomolecules. The significant interactions of both water and ILs form a micellar phase that will be used for drug delivery applications. Water-mediated ILs surrounded the biomolecules and enhance their stability by forming various structures. In this chapter, we aim to discuss the interactions and functions of water and ILs on biomolecules.