The histologic characteristics of small-size prostatic hyperplasia and the effect on low urinary tract symptoms

Abstract

Objective To investigate the histologic characteristics of small-size prostatic hyperplasia(SBPH) and the effect on low urinary tract symptoms (LUTS). Methods 154 patients with SBPH who received transurethral resection of prostate(TURP) were enrolled, preoperative examinations included the obtainment of International Prostate Symptom Score(IPSS), evaluation of the quality of life(QOL), cases of urinary retention, ultrasonography, urodynamic examination, and cystoscopy, postoperative pathology specimen analysis was conducted.The histologic characteristics of small-size prostatic hyperplasia(the histology prostatis and the grade of inflammation) and the effect on LUTS were analyzed. Results A total of 141 cases (91.56%) were diagnosed as SBPH with histological prostatitis, 13 cases(8.44%) in grade 0, 18 cases(11.69%) in grade 1, 76 cases(49.35%) in grade 2 and 47 cases(30.52%) in grade 3.There were statistically significant differences among ages, IPSS, QOL, Qmax, cases of urinary retention between the pure SBPH group and SBPH with HP group(t/χ2=2.610, 6.607, 4.925, 2.673, 4.421, all P 0.05). Conclusion The main pathologic type is stroma hyperplasia(fibrous and smooth muscle) of SBPH, SBPH is mostly complicated with histological prostatitis, which are mostly moderate and severe.The severity of LUTS is positively correlated with the grade of inflammation. Key words: Hyperplasia of prostatic; Histologic; Low urinary tract symptoms