Abstract
1. 1. 24-Tritiolanosterol was prepared from lanosterol. 2. 2. Incubation in vivo of 24-tritiolanosterol with seeds of Pinus pinea yielded labeled 24-ethylidenecholesterol which was identified by ozonolysis to labeled 24-ketocholesterol. 3. 3. The position of the label in 24-ketocholesterol was shown to be C-25 by reduction to the labeled 24-hydroxy derivative followed by dehydration to desmosterol with loss of label. 4. 4. The results are in agreement with the predicted 1,2-H-migration 3 during alkylation of the Δ 24-bond.
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