The efficiency comparision of continuous glucose monitoring system and blood glucose self-monitoring in evaluating blood glucose excursion in type 1 diabetes mellitus complicated with pregnancy

Abstract

Objective To explore the efficiency of continuous glucose monitoring system(CGMS) and blood glucose self-monitoring (SMBG)in evaluating blood glucose excursion in type 1 diabetes mellitus (T1DM) complicated with pregnancy. Methods Twenty-five patients having suffered from T1DM complicated with pregnancy were selected randomly during June 2012 to July 2015. All subjects underwent blood glucose monitoring by CGMS and SMBG for 72 h, including the data of blood glucose before meal, 2 h post-meal blood glucose (2hBG) and blood glucose at 2: 00 AM. Results The level of the highest blood glucose in CGMS was significantly higher than that in SMBG: (10.60 ± 2.11) mmol/L vs. (7.50 ± 1.18) mmol/L, P 0.05. The rate of hypoglycemia(blood glucose<3.3 mmol/L) in CGMS was 4.6%, and in SMBG was 1.9%. Through adjusting the treatment by CGMS, the blood glucose before meal, 2hBG and blood glucose at 2: 00 AM at 49-72 h were significantly lower than that at 0-24 h (P<0.05). Conclusions Compared with SMBG, CGMS has a relatively larger blood glucose monitoring range and can sensitively evaluate blood glucose excursion, CGMS provides a scientific basis to develop a more rational and effective strategies for controlling diabetes. Key words: Diabetes mellitus, type 1; Pregnancy; Continuous glucose monitoring system; Blood glucose self-monitoring