Abstract
Objective To evaluate the effects of Real-Time Continuous Glucose Monitoring in blood glucose fluctuation. Methods One hundreds and twenty-two type 2 diabetes mellitus (T2DM) inpatients who were using insulin were randomly divided into continuous glucose monitoring system (CGMS) group (n=61)and real time CGMS(RT-CGMS) group(n=61). The first day was equipment testing day (d0). The second and third days were observation time (d1 and d2). The CGMS group control blood glucose by finger stick glucose, while the RT-CGMS group by real-time blood glucose curve. Setup the high and low glucose alarm of RT-CGMS. The mean amplitude of glycemic excursions(MAGE), mean blood glucose(MBG), standard deviation of blood glucose(SDBG), absolute means of daily differences(MODD), large amplitude of glycemic excursions(LAGE) and hypoglycemia were calculated within each group and between the two groups. Results (1)Intragroup comparison: RT-CGMS group: the MAGE, MBG, SDBG and LAGE of d1 and d2 were (5.3±3.2) vs (4.2±2.1), (8.6±1.7) vs (8.2±1.5), (2.1±0.9) vs (1.8±0.7), (8.6±3.3) vs (7.5±2.8) mmol/L(F=9.797, 5.852, 20.625, 11.057, respectively, both P 0.05). (2)Intergroup comparison of the difference between d1 and d2: the MAGE and LAGE were 0.7(-0.3-2.0)vs 0(-1.0-1.5), 0.9(-0.7-2.1) vs 0.1(-2.5-1.9) mmol/L(Z= 2.002, 2.023, respectively, both P 0.05). Conclusion Making the blood glucose readjustment plan by RT-CGMS could reduce blood glucose fluctuation in a short time. Key words: Diabetes mellitus, type 2; Continuous glucose monitoring system; Blood glucose fluctuation
Published Version
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