The Efficacy of Tranexamic Acid in the Reduction of Incidence of Dry Socket : Double Blind Study.

Abstract

Introduction :- “Dry Socket” is the common complication which occur after tooth extraction.“Dry Socket” is also known as “Alveolar Osteitis” ,“Alveolitis” or “Alveolitis sicca dolorosa”. An incidence of Dry socket is at its peak in the fourth decade of life. Tranexamic acid is an antifibrinolytic drug. It is used in surgeries with the risk of heavy blood loss. Objectives :- The purpose of the stated study is to judge the efficacy of “tranexamic acid” regarding the reduction of incidence of dry socket following extraction of mandibular molar tooth , in comparison with a placebo.This study was based on two parameters ( pain and halitosis ) . Materials and Methods :- This was an institutional study.It was double blind type of study which was performed on 60 patients. These patients were indicated for extraction of mandibular molar tooth. Patients of 20 to 40 years of age group were eligible for this study and they were randomly selected. Patients in “Case group” were instructed to take tab. Tranexamic acid 500 mg and “Control group” patients were advised to take Tab. Paracetamol 500 mg, one hour prior to extraction. Postoperatively antibiotics and analgesics were prescribed for both group’s patients. Results :- The present study supported that local and systemic administration of tranexamic acid decreases the incidence of “alveolar osteitis” which is associated with the extraction of mandibular molars. Conclusion :- This study proved that there is decrease in the incidence of alveolar osteitis ,i.e, dry socket, if we use tranexamic acid , locally and systemically in patients undergoing extraction with mandibular molar teeth. Keywords:- Alveolar Osteitis,Dry Socket, Halitosis,Pain,Tranexamic acid,