Abstract
Extraction of third mandibular tooth is one of the most commonly performed surgical procedures in oral surgery. One of the most common complications following the extraction of third mandibular molar teeth is dry socket (alveolar osteitis). Dry socket is the delayed healing of the wound of the alveolar bone after dental extractions. The purpose of this study was to determine if the intra-alveolar application of Clindamycin could reduce the incidence of dry socket following the extraction of third mandibular molar tooth. Patients who qualified for the prospective, randomized, double-masked, placebo-controlled trial were randomly divided into 2 groups, each group 30 patients. The first group (30 patients) included smokers and the second group (30 patients) included non smokers. Both groups had the mandibular third molar extracted in both sides at the same time. In total, 120 third molars were extracted. The left site was a study group in which we applied the clindamycin and the right site was a control group. The patients were also divided by gender. Dry socket occurred in 3.3% of cases for patients whom were given Clindamycin, regardless of their smoking habits, as opposed to 31.7% for those who did not receive the antibiotic. Results clearly showed that Clindamycin had a huge impact on reducing dry socket regardless of smoking habits.
Highlights
Dry socket has been treated by many different authors for nearly 110 years and their research has resulted in numerous books published that address the problem from various angles
In patients who were smoker and we apply Clindamycin, dry socket were present in 1% or 3.3% of cases
In patients who were smoker and we didn’t apply Clindamycin, dry socket were present in 13% or 43.3% of cases
Summary
Dry socket has been treated by many different authors for nearly 110 years and their research has resulted in numerous books published that address the problem from various angles Their data indicates that reported cases of dry socket are within a wide range from 1% to 70% [1]. Dry socket occurrence increases more than 20% in patients who smoke more than a pack a day, and 40% in patients who smoke on the day of surgery or the first day after surgery This phenomenon is likely to appear due to foreign substances which act as contaminants in the wound after tooth extraction, and/or due to the inhalation of cigarette which can decompose and slow down wound healing. Anaerobic are the main cause of alveolitis and research has shown the presence of such bacteria as streptococci, fusospirochaetal, treponema denticola, and Bacteroides
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