Abstract
Background: Today, due to the increased drug resistance, plants are used for treatment. The aim of this study was to investigate the effect of ethanol extract of Badrashbu (Dracocephalum moldavica) against strains of antibiotic-resistant Escherichia coli and Klebsiella pneumonia. Methods: Badrashbu plant extracts were prepared using a rotary device. Escherichia coli and Klebsiella pneumonia were isolated from nosocomial infection patients at hospitals of Zabol. The MIC and MBC of Badrashbu extracts in different concentrations of bacteria were determined by disk diffusion method. Results: The results of plant extracts showed that the highest MIC (minimum inhibitory concentration) for E. coli isolates was 20 milligrams per milliliter, and 6 strains were inhibited at this concentration. The highest MIC for K. pneumonia was 40 milligrams per milliliter, and only one strain was inhibited at the concentration. This result can be used to treat the disease. Conclusions: The results of this study showed that Badrashbu extract inhibits Escherichia coli and Klebsiella pneumonia; so it can be used to reduce the plant disease.
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