The effects of portal vein arterialization and party hepatectomy to the hepatocirrhosis

Abstract

Objective To investigate the effects of portal vein arterializations(PVA) on hepatocirrhosis after party hepatectomy, proved that the PVA can increase the regeneration after party hepatectomy, and improve the hepatocirrhosis. Methods The cirrhosis model dogs were allocated randomly into three groups, dogs in group A received PVA after 42％ liver resection, in group B underwent 42％ liver resection only, group C was control group. During the experiment, Before operation, we used the color Doppler senograph to measure the hemodynamic change, the blood was taken to study the alteration of liver function and we use the immunohistochemical technique to exam CD34 of specimens. Results In group A liver weight is significant higher than group B(P＜0.01).The improvement of liver function was also faster in group A. The blood flew of group A was higher than other two groups in 2 ds(P＜0.05). In group A the vascular area defined by endothelial cells that stained for CD34 was higher than two groups. Conclusion ①The portal vein arterializations improve the cirrhosis liver function after partyhepatectomy. ②The portal vein erializations increase the liver regeneration and improve the epatocirrhosis. Key words: Portal vein arterializations; Hepatocirrhosis