The effects of eight weeks anaerobic interval training on serum levels of resistin and vaspin and insulin resistance in obese men with type-2 diabetes

Abstract

Background: Increased secretion of Resistin impaired the insulin function and glucose metabolism, and also Vaspin had an impact on insulin resistance and can play an anti-inflammatory role. This study aimed to investigate the effects of eight weeks anaerobic interval training on serum levels of Resistin and Vaspin and Insulin Resistance. Methods: This quasi-experimental study included obese men with type-2 diabetes that 28 people of them were selected and divided into two group Control and Experimental (n=14). The experimental group performed anaerobic interval exercises for 8 weeks, 3 sessions per week. The blood samples were collected from all the subjects before and after 8 weeks. The assumptions of homogeneity of the slope of the regression line and also the linearity of the relationship between the scores before and after the practice is used and after the confirmation, Covariance analysis test is used (The significance level was considered p≤0/05). Results: The anaerobic interval training has significantly reduce Vaspin (p= <0.0001, f=43.243), Resistin (p=<0.0001, f=40.957) and Insulin Resistance (p=< 0.001, f= 52.024). Conclusion: The anaerobic interval training by weight loss and body fat percentage reduction, leading to significant reduction in serum Resistin and Vaspin and also Insulin resistance, therefore it can be used as a complementary therapy for obese patients and patients with type-2 diabetes.