Abstract
Method The randomized double blind controlled trial of 40 obese adolescent boys aged 14-18 years old were performed on March-May 2011. Subjects were classified into 2 groups, the Vitamin C 500 mg treatment group and the control group which got placebo, twice daily for 8 weeks. The ICAM-1 concentration of both groups was examined before and after the treatment. The data were analyzed with paired sample t-test and independant t-test with significant degree p<0.05.
Highlights
The role of Vitamin C as antioxidant has been known
Obesity is an oxidative stress condition which becomes risk factor of cardiovascular disease, which could be detected through intercellular adhesion molecule-1 (ICAM-1) concentration
The reducing Delta of ICAM-1 concentration in Vitamin C group were higher than placebo group, with ratio 3.9 : 1 (p
Summary
To examine the effect of Vitamin C supplementation on the ICAM-1 concentration on male adolescent obesity in Padang. The reducing Delta of ICAM-1 concentration in vitamin C and placebo group were 187.04 (SD 131.5) ng/ml and 47.91 (SD 62.25) ng/ml, respectively. The reducing Delta of ICAM-1 concentration in Vitamin C group were higher than placebo group, with ratio 3.9 : 1 (p
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