Abstract

The investigation was designed to determine whether the decidual reactions and development of the embryos in the polyethylene IUD horns were comparable to those seen in the control horns. The morphology, glycogen distribution and DNA replication of the 7–9 day old embryos and decidual reactions from the IUD horns were indistinguishable from those of the control horns. However, the per cent of resorption in the IUD horns was significantly greater than that of the controls at days 16–18. All pups were born alive from the three rats allowed to deliver and the polyethylene IUD was still in place in the uterine horn. The results show that the contraceptive action of the polyethylene device extends throughout gestation which is different from the silk thread and copper.

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