Abstract

Background: Vitiligo is a skin disease caused by the destruction of melanocytes with depigmented macular characteristics, multifactorial predisposing factors, and precipitating factors such as trauma, sunburn, stress, and systemic disease. Mimosa Pudica has bioactive compounds that are efficacious for healing wounds, repairing cell tissue, stopping bleeding, asthma, diabetes, jaundice, leprosy, hydrocele, hemorrhoids, fistulas, scrofula, and conjunctivitis. Method: Based on the results of several studies, the technique of collecting & analyzing the cream of Mimosa Pudica leaf extract was by evaluating the cream of the Mimosa Pudica leaves, testing the pH by dissolving the cream product which was diluted using aquadest and then measured with a pH meter. The production of the Mimosa Pudica leaf extract was done by maceration using 96% ethanol. Results: Mimosa Pudica extract succeeded in preserving salak fruit, increasing the regeneration and proliferation of liver cells, overcoming hypopigmentation skin disease, and also inhibiting melanosis in shrimp. Conclusion: Mimosa Pudica (Mimosa pudica L.) The five parts of the plant (i.e. panchang) - leaves, flowers, stems, roots, and fruit belong to the category of powerful antioxidants used as medicine in ethnomedical systems of care.

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