Abstract
The effect of “Melanizol” suppositories on electrolytes level in rats on the background of experimental vaginitis
Highlights
The homeostasis of micro- and macroelements is closely related to the physiological processes occurring in the body
The study was conducted on the model of the vaginitis weighed down with Escherichia coli in female rats
The efficiency of the treatment was determined by changing the levels of Na+, K+, Ca2+, Fe2+ in vaginal fluid and in serum
Summary
As a result of the experiment, it was mentioned that in the composition of blood chemical elements and vaginal content against the background of vaginitis there were various trends in their changes. Significant changes in electrolytes level were not observed in blood, in contrast to the vaginal fluid. It was established that “Melaninol” vaginal suppositories significantly increased the content of Ca2+ and Fe2+, reduced the concentration of K+ and Na+ in comparison with the animals of the control group and exceeded the efficiency of the reference drug Gravagin
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