The effect of long-term consumption of biomass of streptomycetes on conditioned-reflex learning and memory of white rats of different ages

Abstract

The experiments on male white rats revealed that long-term consumption of the biomass of local strains of streptomycetes - Streptomyces massasporeus CNMN-36 and, to a greater extent, Streptomyces fradiae CNMN-Ac-11 isolated from soils of Moldova significantly facilitates the process of learning the skill of active avoidance and slows down the process of extinction of the conditioned reflexes in young and, especially, old animals, which opens up prospects for further study of metabolites of these strains of streptomycetes in order to select substances with neuroprotective and nootropic properties.