Abstract
IT HAS been suspected for some time that the thyroid was at least in part under the control of the nervous system (Uotila, 1940). However, it remained for Greer (1952) to show that anterior hypothalamic lesions in rats prevent the usual thyroid hypertrophy upon the administration of propylthiouracil. Because his animals also showed normal thyroidserum iodide ratios, he postulated the existence of two thyrotrophic hormones. Bogdanove and Halmi (1953) have since confirmed these results, but feel that they can be interpreted as due only to a decrease in the amount of thyrotrophin released in response to propylthiouracil administration. No studies are at present available on the effect of hypothalamic lesions on the thyroid in animals that have not been treated with propylthiouracil. In the course of other investigations on the relationship of the hypothalamus to the anterior lobe of the pituitary, the following studies were carried out in dogs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
