Abstract
Objective To explore the clinical effect of combined octreotide and omeprazole for the treatment of bleeding of esophageal and gastric varices(BEV),analyze its security and provide objective basis for clinical treatment. Methods 92 patients with BEV were randomly selected.According to the treatment methods,they were randomly divided into the control group and observation group.45 cases in the control group were treated with octreotide,47 cases in observation group were treated with omeprazole on the basis of the control group.The main indexes were the treatment effect,48h rebleeding rate,bleeding time and volume of blood transfusion and adverse reaction. Results The total effective rate of the observation group was 93.62%,more than that of control group 82.22%,the difference was statistically significant(χ2= 6.24,P 0.05). Conclusion There is the better for clinical effect of combined octreotide and omeprazole for the treatment of BEV,which could reduce the rebleeding rate,shorten the bleeding time,decrease the volume of blood transfusion,and there was no obvious adverse reactions. Key words: Esophageal and gastric varices; Octreotide; Omeprazole
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