The coding of surprise in auditory cortex of rats

Abstract

Event Abstract Back to Event The coding of surprise in auditory cortex of rats Israel Nelken1* and N. Ta’aseh1 1 Department of Neurobiology and the ICNC, Hebrew University of Jerusalem, Israel We studied the relationships between standards and deviants in the generation of stimulus-specific adaptation in rat auditory cortex. We show that the responses to a low-probability sound depend, although weakly, on the sequence in which it is embedded. When presented alone, deviants evoke somewhat larger responses than when presented in oddball sequences. The decrease in the deviant response in the presence of standards can be attributed to simple adaptation or refractoriness. When presented in the context of a sequence composed of many tones, each of which is rare, deviant responses are on average similar to the responses to deviants in oddball sequences. In about 1/3 of the local field potential recordings, and in more than half of the well-separated single neurons, the responses to deviants in oddball sequences were larger than the corresponding responses among many standards, showing evidence for true deviance detection. We tried to model these results by assuming that SSA is due to adaptation in narrow frequency channels. Such models predict consistently smaller responses to deviants in oddball sequences than to deviants among many standards. To fit our data, it is necessary to assume that in presence of oddball sequences, the adaptation channels become narrower than in other conditions. The narrowing of the adaptation channels for oddball sequences could be a basic mechanism underlying deviance detection. Conference: MMN 09 Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications, Budapest, Hungary, 4 Apr - 7 Apr, 2009. Presentation Type: Oral Presentation Topic: Abstracts Citation: Nelken I and Ta’aseh N (2009). The coding of surprise in auditory cortex of rats. Conference Abstract: MMN 09 Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications. doi: 10.3389/conf.neuro.09.2009.05.066 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 24 Mar 2009; Published Online: 24 Mar 2009. * Correspondence: Israel Nelken, Department of Neurobiology and the ICNC, Hebrew University of Jerusalem, Jerusalem, Israel, israel.nelken@mail.huji.ac.il Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Israel Nelken N. Ta’aseh Google Israel Nelken N. Ta’aseh Google Scholar Israel Nelken N. Ta’aseh PubMed Israel Nelken N. Ta’aseh Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.