The clinical efficacy of Jiegu-Qili tablet combined with intramedullary interlocking nails in the treatment of the fracture of tibia and fibula

Abstract

Objective To explore the effict of Jiegu-Qili tablet combined with intramedullary interlocking nails in the treatment of the fracture of tibia and fibula. Methods A total of 80 patients with fracture of tibia and fibula were selected, and were divided into two groups according to odd and even number of hospitalization. The surgery group (39 patients) was given intramedullary interlocking nails, the surgery and drug group (41 patients) was given Jiegu-Qili tablet combined with intramedullary interlocking nails. The perioperative parameters, the rate of fracture healing, knee scores and complications were evaluated during 12 months. Results The hospitalization (14.43 ± 2.47 d vs. 21.63 ± 3.16 d, t11.385, P0.01) and fracture healing time (5.22 ± 1.05 m vs. 9.75 ± 0.97 m, t20.016, P<0.05) of the surgery and drug group was shorter than that of the surgery group. The fracture healing rate of surgery and drug group (92.7% vs. 76.9%, χ23.894, P0.05) was higher than that of the surgery group. After 6 months surgery, the pain, activity, stability and KSS scores (21.60 ± 1.60 vs. 19.50 ± 1.90, 22.7 ± 2.8 vs.18.70 ± 2.40, 23.50 ± 2.40 vs. 19.40 ± 1.80, 89.20 ± 9.30 vs. 78.00 ± 8.30) of the surgery and drug group were higher than that of the surgery group (P0.05). There was no statistical significance on walking ability between two groups (21.40 ± 2.50 vs. 20.40 ± 2.20, P0.05). During 12 months follow-up, there were no statistical significance on complications between two group (7.3% vs.15.4%, χ21.303, P0.05). Conclusions In summary, the Jiegu-Qili tablet combined with intramedullary interlocking nails had a good therapeutic effect on the fracture of tibia and fibula. It could increase the speed of fracture healing, shorten the hospitalization, reduce the postoperative pain and improve the activity of patients. Key words: Intramedullary interlocking nails; Jiegu-Qili tablet; The fracture of tibia and fibula; Fracture healing rate; Complications