Abstract
Objective To explore the clinical curative effect of different methods on anesthesia radical mastectomy. Methods To choose 120 patients with breast cancer,and divided into epidural group and general anaesthesia group according to different methods of anesthesia randomly, and monitored the changes of blood pressure, heart rate, blood oxygen saturation, norepinephrine, epinephrine and C-reactive protein of all patients during peroperative period, and analyzed the difference between the two groups. Results The vital sign and level of stress hormone of patients of epidural group during peroperative period had no significant difference( all P ＜0.01 ). The vital sign and level of stress hormone of patients of general anaesthesia group intraoperation were significant different compared to preoperation and post operation( all P ＜ 0.01 ). Conclusion Epidural anesthesia had lighter stress reaction and stable vital sign than general anesthesia on radical mastectomy. Key words: Breast neoplasms; Epidural anesthesia; General anesthesia; Stress reaction
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