The clinical application of levonorgestrel-releasing intrauterine system on the treatment of clinical analysis of adenomyosis

Abstract

Objective To investigate the clinical effect of left tactic norgestrel releasing intrauterine system in the treatment of adenomyosis. Methods One hundred and thirty-four patients with diagnosis of uterine adenomyosis were selected as our subjects in Xuanwu Hospital of Capital Medical University from Mar. 2010 to Mar. 2013. They were randomly divided into control group（67 cases）and observation group（67 cases）. Patients in control group were give Gestrinone with oral,and in observation group were give left acetylene connaught progesterone intrauterine placed treatment slow-release system. The information of pain scores,menstruation, uterine volume,endometrial thickness were recorded. Results After treatment,pain score,menstrual quantity, uterine volume and endometrial thickness in observation group were（1. 85 ± 0. 57）,（45. 37 ± 11. 94）ml, （129. 47 ± 8. 67）mm^3 ,（4. 02 ± 2. 04）mm,significantly lower than the control group（（4. 82 ± 2. 07）,（61. 47 ± 12. 07）ml,（148. 54 ± 12. 47）mm^3 ,（6. 35 ± 2. 64）mm）,and the differences between groups were statistically significant（t = 5. 397,6. 047,5. 334,4. 681 respectively;P 〈 0. 05）. Conclusion The therapy of levonorgestrel releasing intrauterine system on treating adenomyosis of uterus is safe and effective. It is worthy of promotion. Key words: Levonorgestrel releasing intrauterine system; Adenomyosis; Pregnant three ketene