The application value of Wb-dwi and Spect on diagnosing osseous metastases

Abstract

Objective To investigate values of Wb-dwi on diagnosis of osseous metastases compared with Spect materials. Methods 20 cases with osseous metastases underwent Wb-dwi and Spect.The bones were divided into 6 groups: skull, collarbone, trunk bone, haunch bone, upper limb bone, lower limb bone.the high uptake regions on Spect and high signal on Wb-dwi for positive groups or positive lesions were recorded.Meanwhile, the total numbers of positive groups and positive lesions in different groups were also recorded.Finally, the diagnostic sensitivity and specificity of Wb-dwi and Spect were calculated, which was based on the total numbers of positive groups. Results Wb-dwi showed 69 positive groups, the numbers of positive lesions in each group were 2, 1, 85, 55, 22, 12.Spect showed 66 positive groups, the numbers of positive lesions in each group were 4, 3, 79, 47, 20, 18.The diagnostic sensitivity and specificity on Spect were 81.1%, 80.3%.The diagnostic sensitivity and specificity on Wb-dwi were 86.9%, 84.3%.No statistical difference was assessed between the sensitivity and specificity of two methods. Conclusion Compared with Spect, the Wb-dwi can show more osseous metastasis lesions and has higher sensitivity on diagnosis osseous metastases.In additional, it can demonstrate primary tumors and extraskeletal metastasis lesions. Key words: Magnetic resonance imaging, diffusion; Tomography, emission-computed, single-photon; Single-photon emission computed tomography