Abstract
目的 评价神经生长因子(NGF)对颈脊髓过伸性损伤的疗效.方法40例颈脊髓过伸性损伤患者随机分为治疗组和对照组,分别以NGF及胞二磷胆碱治疗,观察两组疗效.结果肌力恢复:治疗组总有效率为93.8%,对照组为66.7%,两组比较差异有显著意义(P<0.05).感觉恢复:治疗组总有效率95%,对照组为65%,两组比较差异有显著意义(P<0.05).结论NGF对脊颈髓过伸性损伤疗效肯定,优于胞二磷胆碱.进一步证实外源性NGF可以提高神经损伤处内源性NGF含量和活性。
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