Abstract

The high prevalence and intensity of dental caries, especially among the children’s popu- lation, remains an urgent problem in modern dentistry. Based on previous studies, it can be argued that it is possible to reduce the high incidence of caries by developing effective cariesstatic agents taking into account the individual approach in their application in practice. Purpose — to conduct a comparative analysis of clinical and laboratory indicators of metabolic processes in the oral cavity in caries-resistant children during a shift bite. Materiales and methods. To achieve this goal, a comprehensive clinical and laboratory examination of metabolic processes in the oral cavity was carried out in 60 caries-resistant children during a shift bite: from 7 to 12 years. Statistical analysis was performed using STATISTICA 8.0 software. As a result of the study, clinical and laboratory indicators of metabolic processes in the oral cavity of caries-resistant children were obtained during a shift bite, and the heterogeneity of clinical and laboratory indicators was established. The data obtained in clinically homogeneous groups indicate the possibility of identifying caries predictors and predicting the disease at the preclinical stage of its development. Conclusions. The obtained average figures of clinical and laboratory parameters that make up the center of the cluster can be considered as the norm for the state of caries resistance during the period of a shift bite, the totality of which may allow predicting the carious process even before its clinical manifestation.

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