Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age. The pathogenesis of PCOS is not clear, more and more studies show that PCOS patients have immune dysfunction. Helper T cell type 1(Th1) and helper T cell type 2(Th2) mediate cellular and humoral immune responses in vivo, and they regulate and restrict each other. Normally, Th1/Th2 is in equilibrium in the body. It is found that PCOS shifts from Th1/Th2 balance to Th1, which can cause metabolic disorder and ovulation disorder. It suggests that the break of immune balance in PCOS patients may be the cause of complications. Currently, drugs are used to balance Th1 and Th2 cell states to improve clinical symptoms. Key words: Polycystic ovary syndrome; Th1/Th2 imbalance; Insulin resistance; Treatment
Published Version
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