Th e risk of developing arterial hypertension in workers exposed to fi brogenic dust in asbestosconcentrating industry

Abstract

Relevance. Occupational factor nowadays is considered an important condition of cardiovascular risk increase, including arterial hypertension growth. With this, study of work conditions infl uence on probable arterial hypertension development and other cardiovascular risk factors appears topical.Objective. To construct prognostic model of probable arterial hypertension development in workers of asbestos-concentrating plant, who are exposed to higher concentration of fi brogenic dust containing chrysotile.Materials and methods. Main group (161 individuals) comprised patients with diagnosed occupational disease (asbestosis), reference group included workers (222 individuals) with long length of service, without occupational diseases. Th e groups matched in age, sex, length of exposure to hazards, smoking index.Results. Findings are high occupational conditionality of left ventricle hypertrophy (relative risk 3.217, att ributable fraction 54.32%). Revealed factors that promote occupationally conditioned arterial hypertension (asbestosis, obesity, increased serum glucose, coronary heart disease, increased heart rate, lower saturation) served as a basis for prognostic model design by logic regression.Conclusion. Mathematic modelling helps to define contribution of occupational and non-occupational factors into arterial hypertension development in workers exposed to fi brogenic dust. Dust factor is an additional risk factor in arterial hypertension development am ong workers engaged into asbestos-concentrating production.