Abstract
Background: World Health Organization (WHO) estimates that 2 billion people in the world have zinc deficiency. Clinical manifestation of zinc deficiency includes immune system dysfunction, increase of oxidative stress, and release of proinflammatory cytokines. Oxidative stress is one of main factors that plays important role in various autoimmune diseases such as vitiligo. Discussion: Vitiligo is the most common depigmentation disease caused by melanocyte damages which characterized by depigmentation macule or patch on the skin or mucous membranes. Treatment of vitiligo is still considered a challenge, and various treatment modalities show varying results. Zinc is a micronutrient and antioxidant that posseses antiapoptotic activity by influencing melanogenesis and eliminating free radicals. Conclusion: Zinc inhibits oxidative stress and prevent melanocyte damage so it can bd considered as an adjuvant treatment for vitiligo.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
