Synthesis, Spectroscopic, Magnetic and Biological Activity of Cr(III) and Fe(III) Complexes with Amino Acids and Heterocyclic Amines

Abstract

The synthesis and investigation of the electronic properties of Cr(III)/Fe(III) metal complexes with amino acids and heterocyclic amines has been carried out on the basis of metal estimation, conductivity and magnetic measurements, infrared spectra and electronic spectra studies. The complexes were of [M(X)L] type, where M = Cr(III)/Fe(III) and X= deprotonated amino acids as a primary ligand, such as Glycine, Alanine, Leucine, Cysteine; L= heterocyclic amines as a secondary ligand, such as Pyridine, 8-hydroxyquinoline. Antibacterial activity of the complexes has been examined against six (gram positive and gram negative) pathogenic bacteria by disc diffusion method and compared with that of standard antibiotic (Kanamycin). The Fe(III) complexes was found to have strong antibacterial activity against the tested bacteria.