Abstract
Objective: Cancer has remained a challenge to the healthcare system due to changes in eating habits and lifestyle, tremendous side effects of chemotherapy, and resistance to existing treatment due to mutations, which creates difficulty in identifying specific targets. Chemistry and Methodology: In this study, equimolecular amounts of reagents were used to synthesize substituted isoxazoles from alpha-beta unsaturated intermediates. Result: Compounds were collected in varying amounts of yield. Spectroscopic data supports the formation of compounds. Compound Id shows GI50 of 46.3 μg/mL against MDA-MB-231. Conclusion: The effective synthesis of novel derivatives has opened up exciting new avenues for medicinal research; one of these compounds has moderate anticancer properties.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.