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PDF Availablehttps://doi.org/10.1016/j.jfluchem.2017.12.012
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Cite Journal: Journal of Fluorine Chemistry |  Publication Date: Dec 20, 2017 |
 Citations: 5 |  License type: cc-by-nc-nd |
Affiliation: Durham University
Multi-component Mannich reactions between 2-fluoro-ethylacetoacetate or dimethyl-2-fluoromalonate ester, aldehyde and amine components allowing convenient synthesis of β-fluoro(dicarbonyl)ethylamine systems using both batch and continuous flow techniques are reported.
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