Abstract
The tridentate ligand 1,3-bis(benzimidazol-2-yl)-2-oxopropane (OBB) and its manganese(II) picrate complex, with composition [Mn(OBB)·(EtOH)2·(H2O)](pic)2·2EtOH (pic = picrate), have been synthesized and characterized. Single-crystal X-ray diffraction revealed that the Mn(II) ion is six-coordinated with a N2O4 ligand set, resulting in a distorted octahedral coordination geometry. The interaction of the ligand and its Mn(II) complex with calf thymus DNA was investigated by electronic absorption titration and viscosity measurements. The experimental results suggest that the ligand and its Mn(II) complex bind to DNA via an intercalation binding mode, and their binding affinity to DNA follows the order of complex > ligand.
Published Version
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