Abstract
Developing a biomaterial with inherent magnetic properties that allows easy magnetic resonance imaging (MRI) without contrast agents would greatly benefit the field of orthopedics. This study synthesized a magnetic gadolinium-doped beta-tricalcium phosphate (Gd-β-TCP) biomaterial and characterized its biocompatibility and magnetic properties. Three synthesis methods were used and compared to find the best method. MRI tests confirmed that the material had higher magnetization than pure β-TCP, while cytocompatibility tests examined its effect on osteoblast cells, confirming its suitability for bone regeneration. In conclusion, the synthesized Gd-β-TCP material can be used in bone implant applications to facilitate postoperative examination of the implant site.
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