Abstract
Abstract Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles, and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber's geometry and nanoparticles' coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.
Published Version
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