Abstract
Objective: To determine the frequency of complete tumor excision by endoscopic skull base (transsphenoidal) approach in pituitary adenoma patients presenting to a neurosurgical department.
 Materials & Methods: This descriptive case series was conducted at the Department of Neurosurgery Unit II, Lahore General Hospital Lahore from May 2019 to November 2019. The study included60 patients with pituitary adenoma from the outpatient department who qualified for the inclusion criteria. All patients went through the endoscopic binarial transsphenoidal approach for pituitary adenectomy. All patients were treated according to the department protocols and were followed for 6 weeks to determine the outcome i.e. no residual tumor left as determined by Magnetic Resonance Imaging.
 Results: The mean age of pituitary adenoma patients studied was 50.02 ± 8.2 years. 43 patients (71.7%) were male.56 patients (93.3%) showed complete resection on MRI using the endoscopic binarial transsphenoidal approach. The outcome was not affected by patients' gender and age. Tumor size significantly affected the outcome i.e. complete resection.
 Conclusion: It is concluded that the endoscopic skull base (transsphenoidal) approach for excision of pituitary adenomas gives desirable results as depicted by 93.3% success rate in terms of complete resection of the tumor. We did not observe a significant effect of patients' gender and age on the clinical outcome in the studied sample of the population.
Highlights
Pituitary adenomas are among the most frequently reported tumors of sella turcica
Endoscopy is increasingly used in pituitary adenoma surgery with promising results and lesser complications
Patients included who were with the diagnosis of pituitary adenoma by Magnetic Resonance Imaging (MRI)
Summary
Pituitary adenomas are among the most frequently reported tumors of sella turcica. Approximately 10% of all brain tumors comprise pituitary adenomas.[1,2] A study in England reported a four times higher prevalence of pituitary adenomas when compared with previous318 Pak. Pituitary adenomas are among the most frequently reported tumors of sella turcica. Rizwan Ahmed Khan, et al: Surgical Outcome of Pure Endonasal Transsphenoidal Approach for Pituitary Tumors estimates.[3] Herman Schloffer first introduced trans sphenoidal method for resection of pituitary adenoma about 100 years ago.[4] The excision of pituitary tumors is modified after the introduction of a transnasal endoscopic approach to the sellaturcica.[4] The endoscope provides a better view of the sella turcica. The endoscopic approach provides an exceptional panoramic visualization when compared with the conventional conical outlook of the microscopic view.[5,6] The complete excision of the tumor is important to optimize the integrity of the neural structure by releasing the pressure effects.[7] Other techniques for tumor resection include the microscopic endonasal transsphenoidal approach and microscopic sublabial transsphenoidal approach
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
