Abstract

One of the main complications during early embryogenesis and placentation is placental dysfunction. Under the influence of various factors, namely infectious ones, which depending on biological specificity negatively affect the reproductive cells of parents, the development of the embryo, the formation of trophoblast and placenta, which in turn leads to disorders of the placental complex function and gestational complications during pregnancy. Due to the expansion of diagnostic capabilities for detecting disorders of the placenta function, as well as the emergence of new data on the mechanisms of blood flow regulation in the placenta to evaluate the functional state of the feto-placental complex (FPC) at the phase of the primary placental dysfunction formation in women with pelvic inflammatory diseases, we identified Doppler image of the blood flow features (ovarian artery, inter-villous space) in women of the main and control groups. According to the objective, an ultrasound examination of 67 women in 6-7 and 12-14 weeks of gestation was performed. The main group included 37 women with signs of inflammatory diseases of the female genital organs, and the control group included 30 practically healthy women. Obtaining new data on the mechanisms of blood circulation regulation in the ovarian artery and inter-villous space at the stage of placental complex formation during physiological and complicated pregnancy will enable to supplement the issues of pathogenesis of development and prevention of placental dysfunction.

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