Abstract
This paper reports on the performance of a subterahertz (THz) liquid sensor tool coupled to a microfluidic platform. Contactless and on-line measurements are demonstrated for the determination of ethanol concentration and controlling by a micromixer device. The authors have developed a label-free chemical sensing methodology coupling a subterahertz sensor technology to microfluidic devices fabricated on glass and polydimethylsiloxane. They demonstrated on-line sensing and control of ethanol concentration on demand. The THz-microfluidic sensing strategy represents a versatile tool for fast and easy integration in microfluidic devices, for concentration detection and linear control of binary mixture concentration in a contactless mode using microreactors in laminar flow and fast mixing mechanism by convection.
Highlights
The ability to perform chemical and biological analyses on micro- and nanoscales using miniaturized devices has received increasing attention in recent years
This paper reports on the performance of a subterahertz (THz) liquid sensor tool coupled to a microfluidic platform
We worked on the development of a flexible platform for performing microfluidic experiments with an embedded spectroscopic sensor, which allows contactless measurements and noninvasive in liquids characterization on-line. We demonstrated such capabilities through various measurements in microfluidic environment operating in a laminar flow, with Reynolds number smaller than 13 and Peclet number larger than 25 700 in the micromixer and ten times smaller in the joint section Pe 1⁄4 2383
Summary
The ability to perform chemical and biological analyses on micro- and nanoscales using miniaturized devices has received increasing attention in recent years. The microfluidics appears as an emerging technology, which allows the manipulation of very small volumes of fluids inside the microchannels It takes advantages of using much less reagents, using low-cost materials and fabrication to produce miniaturized, portable, and reusable devices, fast temperature change, ease in applying higher electric fields, occupied area of a few square centimeters, reactions in flow systems, potentially to follow reactions running in real time.. It is possible to perform high throughput chemical reactions, in microfluidics devices, called as lab-ona-chip or micrototal analyses systems in literature. These can incorporate multiple stages, such as mixing, separation, heating, and detection, for applications in different fields, such as fluid physics, biology, biomedicine, biotechnology, chemistry, and pharmacy.. These can incorporate multiple stages, such as mixing, separation, heating, and detection, for applications in different fields, such as fluid physics, biology, biomedicine, biotechnology, chemistry, and pharmacy. This technology has the capacity to use tiny quantities of samples and reagents to detect, synthesize, and separate compounds with high resolution and sensitivity, or to exploit the flow patterns occurring at the microchannels. In addition, with single-phase
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