Abstract
1,2-dodecanediol otherwise known as lauryl glycol (LG), a skin conditioning agent in many skin cosmetics was recrystallized from chloroform on to a number of different technical substrates to understand how material properties affect their recrystallization behavior at the molecular level. For this purpose, four different technical substrates were chosen based on their polarity and crystallinity. On highly oriented pyrolytic graphite or HOPG (nonpolar, crystalline), LG recrystallization formed parallelogram-like-structures in the initial stage. On nonpolar, amorphous substrate like glassy carbon (GC) stalactite-like-structures were observed. Contrary to this, on polar substrates like mica (polar, crystalline) and glass (polar, amorphous), LG molecules were recrystallized as thin film. The morphological changes of LG at different time intervals were investigated and their mechanism of recrystallization on all the substrates is discussed in detail for the first time. Direct view of the recrystallization process at the molecular level on different technical substrates can be used as a model in understanding how these molecules as a constituent in skin cosmetic products behave, when applied to skins of varying physical and chemical barrier ultimately helping in better cosmetic development.
Highlights
Straight-chain 1,2-alkanediols are multifunctional ingredients with moisturizing and antimicrobial activities [1,2,3,4,5,6,7]
A series of Atomic force microscopy (AFM) images at different time intervals demonstrating the morphological changes after recrystallizing 0.4 mg/mL Lauryl glycol (LG) molecules from chloroform on to a freshly cleaved HOPG surface is presented in figure 1
Structures which look like parallelograms, from here onwards will be called as parallelogram-like-structures appeared on the HOPG surface in the initial stages of recrystallization
Summary
Straight-chain 1,2-alkanediols are multifunctional ingredients with moisturizing and antimicrobial activities [1,2,3,4,5,6,7]. The tapping mode was developed to minimize the lateral force during scanning and is the most dominant mode in AFM field at this moment routinely allowing high resolution topographic imaging of sample surface that are damaged, loosely hold to the substrate or difficult to image by contact mode. In this mode, the cantilever is oscillated at or near its resonance frequency. As the cantilever approaches the sample surface, depending on the interaction between sample and cantilever, the cantilever undergoes a change in amplitude and frequency
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