Study on the relationship between left atrial diameter with serum uric acid level in male patients with essential hypertension

Abstract

Objective To study the relationship between serum uric acid and left atrial size in male patients with essential hypertension. Methods From June 2015 to December 2016, 298 males with essential hypertension in the People′s Hospital of Guangdong Province were selected.They were divided into normal left atrial group and enlarged left atrial group based on the size of left atrial diameter.The fasting blood glucose, serum lipid, serum uric acid, hepatic and renal function and blood pressure were measured by routine methods, and multivariate logistic regression was used to analyze. Results The average age and serum uric acid level of 298 males with essential hypertension were (55.29±8.48) years old and (488.93±112.46)μmol/L.There were 47 cases with enlarged left atrial.The serum uric acid level in the enlarged left atrial group was significant higher than that in the normal left atrial group[(512.21±90.82)μmol/L vs.(474.38±94.26)μmol/L, t=9.34, P<0.001]. Pearson correlation analysis showed that serum uric acid level was positively associated with left atrial diameter(r=0.589, P<0.001). Multiple logistic regression analysis showed that the serum uric acid level was a risk factor for enlarged left atrial(OR=1.894, 95%CI: 1.13, 2.69; P<0.001). Conclusion Serum uric acid level is positively correlated with left atrial size in male patients with essential hypertension, and is a risk factor for enlarged left atrial. Key words: Atrial funcyion, left; Hypertension; Serum uric acid; Men