Abstract
Background: Individualized corneal refractive surgery requires an understanding of the basis of higher-order aberrations before surgery. To investigate the characteristics and distribution of anterior surface wavefront aberrations in patients suitable for corneal refractive surgery. Methods: A total of 121 myopic patients (121 eyes, 18 - 45 years old) who underwent corneal refractive surgery were recruited from January to May 2016 at Affiliated Hospital, Yanbian University. Patients were randomly selected by the Pentacam anterior segment analysis system with a spherical equivalent (SE) of -0.25 to -10.00 D. The corneal anterior aberrations (total higher-order aberration; spherical aberration; Coma; Trefoil) and Q and K values were detected, and a correlation analysis of the relevant parameters was carried out. Results: The root-mean-square (RMS) of the third to sixth order aberrations of the corneal anterior wavefront aberrations at a 6 mm analysis diameter showed a decreasing trend in patients suitable for the corneal refractive surgery, and the RMS of the third order aberrations accounted for 62.92% of the total HOAs. The coma ratio (coma/total cornea higher-order aberrations) was increased with the increasing diopters, while the spherical aberration ratio (spherical aberration/total cornea higher-order aberrations) was not changed. In addition, the spherical aberration was 0.203 ± 0.082 μm (range: 0.061 to 0.503 μm), and the Q30 was -0.19 ± 0.03 (range: -0.58 to 0.31). There were significant differences in the coma aberrations of preoperative corneal anterior surface (3, 1) between the low, middle and high myopia groups (P = 0.013). The spherical equivalent was positively correlated with the corneal coma of the anterior corneal surfaces (R = -0.241, P = 0.009), and the Q value was positively correlated with the total higher-order aberrations (R = 0.326, P Conclusions: Individual wavefront aberrations on the anterior surfaces of the cornea are comparatively different, and the Zernike coefficients are related to the degree of myopia. Spherical aberrations are the most overriding aberrations of the cornea.
Highlights
Wavefront aberration is the deviation between the actual and the ideal wavefront, including wavefront aberrations of the cornea and inner eye, which are the main factors affecting visual quality
There were some changes in spherical aberrations and coma aberrations before corneal refractive surgery: the spherical aberrations accounted for 53.3%, 52.1% and 42.5%, in the low, moderate and high myopia groups, respectively, and the coma aberrations were 42.2%, 56.4% and 62.3%, respectively
At a 6 mm analysis diameter, the total corneal higher-order aberration was 0.351 ± 0.152 μm, and the spherical aberration was 0.203 ± 0.082 μm, in which 71.6%, 19.2% and 32.7% of the patient eyes were at 0.15 - 0.30 μm, 0.25 - 0.30 μm and 0.20 - 0.25 μm, respectively
Summary
Wavefront aberration is the deviation between the actual and the ideal wavefront, including wavefront aberrations of the cornea and inner eye, which are the main factors affecting visual quality. Conventional corneal laser refractive surgery significantly improves higher-order aberrations and corrects low order aberrations, and significantly improves visual quality [2] [3] [4]. To investigate the characteristics and distribution of anterior surface wavefront aberrations in patients suitable for corneal refractive surgery. The corneal anterior aberrations (total higher-order aberration; spherical aberration; Coma; Trefoil) and Q and K values were detected, and a correlation analysis of the relevant parameters was carried out. Results: The root-mean-square (RMS) of the third to sixth order aberrations of the corneal anterior wavefront aberrations at a 6 mm analysis diameter showed a decreasing trend in patients suitable for the corneal refractive surgery, and the RMS of the third order aberrations accounted for 62.92% of the total HOAs. The coma ratio (coma/total cornea higher-order aberrations) was increased with the increasing diopters, while the spherical aberration ratio (spherical aberration/total cornea higher-order aberrations) was not changed.
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