Abstract
BackgroundTo investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic patients.MethodsThis retrospective study included 197 eyes (101 patients) undergoing SMILE surgery. According to the preoperative spherical equivalent (SE), treated eyes were divided into two groups: a high myopic group (more than − 6.0 D, Group H) and a mild to moderate myopic group (less than − 6.0 D, Group M). Corneal HOAs of the anterior surface, posterior surface, and total cornea were measured using a Scheimpflug camera preoperatively and 3 months postoperatively. Pearson’s correlation analysis was conducted to determine relationships between corneal aberrations and the SE.ResultsThere were no significant differences in third-order to eight-order aberrations (RMS HOAs) of the anterior surface, posterior surface, and total corneal between the two groups before SMILE surgery. However, after SMILE, anterior and total corneal HOAs, especially vertical coma and spherical aberrations, significantly increased in both groups (p < 0.0167), whereas posterior corneal HOAs remained relatively stable (p > 0.0167). The induction of HOAs was significantly greater in Group H than Group M postoperatively (p < 0.0167). Changes in anterior surface and total corneal HOAs, especially vertical coma and spherical aberrations, were related to the SE (p < 0.05).ConclusionsAnterior and total corneal HOAs, particularly vertical coma and spherical aberrations, significantly increased after SMILE in both groups, whereas posterior corneal HOAs remained stable. Aberration changes were related to SE.Trial registrationRetrospectively registered. ChiCTR-ORC-17011040. Registered 1 April 2017. Name of registry: The observation of clinical results after corneal refractive surgery. Data of enrolment of the first participant to the trial: 15 December 2016.
Highlights
To investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic patients
There were no significant differences in coma and spherical aberrations of the anterior surface between the two groups preoperatively (p > 0.0167)
There was a significant increase in vertical coma (Z3,1) and spherical aberrations (Z4, 0) in the two groups 1 and 3 months postoperatively (p < 0.0167)
Summary
To investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic patients. Higher-order aberrations (HOAs) increase after successful refractive surgery and influence the vision quality of patients. Previous studies indicated that posterior corneal HOAs influenced corneal biomechanical responses and provided valuable information in determining the cause of poor vision quality after corneal refractive surgery [2, 3]. A few studies have compared anterior, posterior, and total corneal HOAs following different refractive surgery procedures [2, 3, 12]. We compared HOAs of the anterior surface, posterior surface, and total cornea after SMILE surgery for high myopia and mild to moderate myopia
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