Abstract
Objectives : The aim of our study was to determine the role of fenugreek seed powder on serum lipid profile in patients of type 2 Diabetes Mellitus. Methods : Of all the patients attending the medicine OPD of Muzaffarnagar Medical College & Hospital from June 2012 August 2014, 100 patients of Type II Diabetes Mellitus were selected randomly, including both male and female of age group 40-75 years. They were then divided into 2 groups, study group and control group. One group consisting of fifty patients was given only Anti-Diabetic treatment (control group) and another group consisting of fifty patients was given 50gm of powdered fenugreek seeds in two divided doses in their diet along with their Anti-Diabetic treatment (study group). All the hundred patients included in the study were on lifestyle modification also. Their serum fasting lipid profile levels were repeated every two months for a study period of six months and then the data from study and control group was evaluated and compared. Results : There was significant reduction in total cholesterol, low density lipoprotein, very low density lipoprotein, and triglyceride and significant rise in the high density lipoprotein levels. Conclusion : The result support the hypothesis and the research question that fenugreek supplement with usual medical care for Type II Diabetes Mellitus is more effective than the usual medical care alone. Therefore, it is recommended that fenugreek supplementation is safe and may be considered in Diabetic patients as a potential means to lower the serum lipid profile level.
Highlights
Type 2 Diabetes Mellitus is one of the most prevalent and fastest growing diseases in India
Hyperlipidaemia is the current medical as well as social problem, specially associated with diabetes mellitus leading to increasing morbidity and mortality[2]
It has been attributed that the antihyperglycemic effect of these plants is due to their ability to restore the function of pancreatic tissue by causing an increase in insulin output or inhibit the intestinal absorption of glucose or to the facilitation of metabolites in insulin dependent processes
Summary
Type 2 Diabetes Mellitus is one of the most prevalent and fastest growing diseases in India. Hyperlipidaemia is the current medical as well as social problem, specially associated with diabetes mellitus leading to increasing morbidity and mortality[2]. In spite of the presence of known antidiabetic medicine in the pharmaceutical market, remedies from medicinal plants are used with success to treat this disease[1]. It has been attributed that the antihyperglycemic effect of these plants is due to their ability to restore the function of pancreatic tissue by causing an increase in insulin output or inhibit the intestinal absorption of glucose or to the facilitation of metabolites in insulin dependent processes. Treatment with herbal drugs has an effect on protecting beta cells and www.ssjournals.com
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