Abstract
Abstract The reaction of the extremely stable free radical, 2,2,6,6-tetramethyl-4-oxopiperidine-1-oxyl (I), was carried out with benzenethiols (IV). The formation of diphenyl disulfides (VI), benzenesulfinic acids (VII), and 1-(p-substituted benzenesulfinyl)-2,2,6,6-tetramethyl-4-oxopiperidines (X) from the above reaction shows that the radical (I) can act as a hydrogen-abstracting agent, an oxidizing agent, and a radical scavenger. Possible mechanisms for the coupling reaction of the radical (I) with the S-radicals (V) to give the sulfinamides (X) were discussed. A substituent effect was observed in the formation of the disulfides (VI). The N-oxyl radical (I) and another stable free radical, such as 2,6-di-t-butyl-4-methylphenoxyl radical (XXV), were shown to react with the S-radical (XVII) derived from thiamine (XIV) to give new types of thiamine derivatives, S-(2,2,6,6-tetramethyl-4-oxopiperidino) thiamine (XX) and S-(2,6-di-t-butyl-4-methylphenoxy)thiamine (XXVI) respectively.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call