Studies directed toward the preparation of key intermediates for the synthesis of trisporic acids and cassiol

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Abstract An enantioselective synthesis and resolution of the key White intermediate (3) for the synthesis of trisporic acids are described. Attempts to develop a synthetic route toward the antiulcerogenic compound cassiol (2) by an olefination reaction of 3 and an alternative sequence involving a Michael addition followed by an aldol condensation of an open substrate, are also reported.