Abstract
As the tissue engineering scaffolds, the pore structure and condensed structure of silk fibroin scaffolds should be adjusted and controlled. In this study, Antheraea pernyi/Bombyx mori (A. p/B. m) silk fibroin blend scaffolds were prepared by freeze-drying. The influence of blend ratios on the pore structure and condensed structure of the scaffolds was investigated. The results showed that the average pore diameter of the blend scaffolds changed from 56 to 326 μm. Due to the difference of properties and the macromolecules aggregation status of two silk fibroin solutions, the pore diameter, content of α-helix and crystallinity of the scaffolds decreased with the increasing of the proportion of B. m silk fibroin. By adjusting the blend ratios, the pore structure and condensed structure of A. p/B. m silk fibroin blend scaffolds could be controlled.
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